{"id":11974,"date":"2023-10-06T10:41:23","date_gmt":"2023-10-06T08:41:23","guid":{"rendered":"https:\/\/www.retriever-klub.cz\/?p=11974"},"modified":"2026-02-25T11:49:35","modified_gmt":"2026-02-25T10:49:35","slug":"stargardtova-choroba-stgd-u-plemene-lr","status":"publish","type":"post","link":"https:\/\/www.retriever-klub.cz\/en\/stargardtova-choroba-stgd-u-plemene-lr\/","title":{"rendered":"Stargardtova choroba (STGD) u plemene LR"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>Stargardtova choroba (STGD)<\/strong><\/p>\n<p class=\"wp-block-paragraph\">Stargardtova choroba je d\u011bdi\u010dn\u00e9 o\u010dn\u00ed degenerativn\u00ed onemocn\u011bn\u00ed s\u00edtnice, zp\u016fsobuj\u00edc\u00ed podstatn\u00e9 zhor\u0161en\u00ed zraku u labradorsk\u00fdch retriever\u016f. Jedn\u00e1 se o nemoc, zp\u016fsobenou mutac\u00ed genu pro tvorbu membr\u00e1nov\u00e9ho proteinu sv\u011btlo\u010div\u00fdch element\u016f. Na s\u00edtnici se d\u00edky tomu ukl\u00e1daj\u00ed v\u00a0retin\u00e1ln\u00edm epitelu metabolity vitam\u00ednu A a lipofuscinu. V\u00edce trp\u00ed \u010d\u00edpky, kter\u00e9 jsou d\u016fle\u017eit\u00e9 pro vn\u00edm\u00e1n\u00ed barvy, m\u00e9n\u011b ty\u010dinky reaguj\u00edc\u00ed na sv\u011btlo.<\/p>\n<p class=\"wp-block-paragraph\">Projevy jsou patrn\u00e9 p\u0159edev\u0161\u00edm u star\u0161\u00edch ps\u016f, u kter\u00fdch lze pozorovat roz\u0161\u00ed\u0159en\u00e9 zornice a abnorm\u00e1ln\u00ed reakci na osln\u011bn\u00ed. V\u00fdrazn\u011b je naru\u0161eno jak denn\u00ed vid\u011bn\u00ed, tak vid\u011bn\u00ed za \u0161era.<\/p>\n<p class=\"wp-block-paragraph\">Vzhledem k\u00a0tomu, \u017ee se se jedn\u00e1 o onemocn\u011bn\u00ed s\u00a0autosom\u00e1ln\u011b recesivn\u00ed d\u011bdi\u010dnost\u00ed, plat\u00ed zde tedy stejn\u00e9 sch\u00e9ma v\u00a0chovu jako u v\u011bt\u0161iny genetick\u00fdch\u00a0 chorob ps\u016f: nespojovat dva p\u0159ena\u0161e\u010de!<\/p>\n<p class=\"wp-block-paragraph\">V\u00a0posledn\u00edch letech je mo\u017en\u00e9 toto onemocn\u011bn\u00ed geneticky testovat, b\u00fdv\u00e1 sou\u010d\u00e1st\u00ed velk\u00fdch panel\u016f ve v\u011bt\u0161in\u011b laborato\u0159\u00ed, nap\u0159. Genomia, Laboklin, UCD, Wisdom.<\/p>\n<p class=\"wp-block-paragraph\">Vzhledem k\u00a0tomu, \u017ee testov\u00e1n\u00ed na toto onemocn\u011bn\u00ed nen\u00ed je\u0161t\u011b rutinn\u00ed z\u00e1le\u017eitost\u00ed, nen\u00ed zcela zn\u00e1m jeho v\u00fdskyt.<\/p>\n<p class=\"wp-block-paragraph\">R\u00e1da bych zmapovala situaci populace v\u00a0\u010cR a proto bych poprosila o zasl\u00e1n\u00ed test\u016f ty, kte\u0159\u00ed maj\u00ed u sv\u00fdch chovn\u00fdch labrador\u016f Stargardtovu chorobu otestovanou.<\/p>\n<p class=\"wp-block-paragraph\">P\u0159edem velice d\u011bkuji,<\/p>\n<p class=\"wp-block-paragraph\">Iva V\u00edtkov\u00e1, poradce chovu pro LR<\/p>\n<p class=\"wp-block-paragraph\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-11977\" src=\"https:\/\/www.retriever-klub.cz\/wp-content\/uploads\/2025\/12\/received_1493719470965679-2-222x300.jpg\" alt=\"\" width=\"222\" height=\"300\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Stargardtova choroba (STGD) Stargardtova choroba je d\u011bdi\u010dn\u00e9 o\u010dn\u00ed degenerativn\u00ed onemocn\u011bn\u00ed s\u00edtnice, zp\u016fsobuj\u00edc\u00ed podstatn\u00e9 zhor\u0161en\u00ed zraku u labradorsk\u00fdch retriever\u016f. Jedn\u00e1 se o nemoc, zp\u016fsobenou mutac\u00ed genu pro tvorbu membr\u00e1nov\u00e9ho&#8230;<\/p>\n","protected":false},"author":2,"featured_media":11977,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[6,4],"tags":[],"class_list":["post-11974","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-informace-pro-chovatele","category-novinky"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/posts\/11974","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/comments?post=11974"}],"version-history":[{"count":1,"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/posts\/11974\/revisions"}],"predecessor-version":[{"id":13723,"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/posts\/11974\/revisions\/13723"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/media\/11977"}],"wp:attachment":[{"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/media?parent=11974"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/categories?post=11974"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.retriever-klub.cz\/en\/wp-json\/wp\/v2\/tags?post=11974"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}